ANTIOXIDANT EVALUATION AND MOISTURIZING EFFICACY OF FACIAL TONER PREPARATIONS FROM ASAM KANDIS ETHANOL EXTRACT

FORMULASI DAN EVALUASI TONER WAJAH ASAM KANDIS SEBAGAI ANTIOKSIDAN DAN PELEMBAB ALAMI DARI EKSTRAK ETANOL ASAM KANDIS (Garcinia xanthochymus) Hook.f. ex T. Anderson

Authors

  • Hanafis Sastra Winata hanafis Institut Kesehatan Helvetia
  • Muhammad Andry Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Sriwijaya, Indralaya, Sumatera Selatan, Indonesia
  • Muhammad Amin Nasution Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, 23111, Indonesia
  • Bunga Olfa Deska Siregar Olfa Deska Siregar Universitas Syiah Kuala

DOI:

https://doi.org/10.51771/fj.v6i1.1900

Keywords:

Toner Wajah , Asam Kandis, Pelembab, Antioksidan

Abstract

Buah asam kandis memiliki berbagai aktivitas seperti antioksidan dan antimikroba. Tujuan penelitian ini untuk melakukan uji efektivitas dan antioksidan sediaan face toner ekstrak etanol buah asam kandis (Garcinia xanthochymus Hook.f. Ex T. Anderson) sebagai pelembap. penelitian yang dilakukan meliputi identifikasi tumbuhan, pembuatan simplisia, karakteristik simplisia, pembuatan ekstrak, pembuatan sediaan face toner dengan konsentrasi 2%, 4% dan 6% dan evaluasi mutu fisik sediaan yaitu pengukuran pH, pengamatan organoleptis, pengamatan homogenitas dan pengamatan stabilitas. Selain itu, dilakukan uji efektivitas sediaan face toner sebagai pelembap dan uji antioksidan dengan menggunakan metode ABTS. Formulasi sediaan face toner berbentuk cair, homogen, berwarna cokelat muda hingga cokelat tua, aroma khas fregrance, pH aman dalam rentan 4,5-6,5 dan tidak mengiritasi kulit. Pada uji efektivitas yang dilakukan selama 4 minggu, didapatkan hasil bahwa peningkatan kadar air pada F0 3% ke 9,3%, F1 (2%) 3% ke 13,6%, F2 (4%) 3% ke 15,6% dan F3 (6%) 3% ke 19%. Dari pengukuran antioksidan didapatkan nilai IC50 pada F1 (2%) 131,6263 dengan kategori lemah, F2 (4%) 120,8348 dengan kategori lemah dan F3 (4%) 98,6268 dengan kategori kuat. Berdasarkan penelitian yang telah dilakukan didapatkan hasil bahwa, perbedaan konsentrasi ekstrak etanol buah asam kandis tidak mempengaruhi mutu fisik sediaan. Semakin tinggi konsentrasi ekstrak etanol buah asam kandis maka semakin tinggi efektivitasnya dalam melembapkan kulit dan semakin tinggi konsentrasi ekstrak maka nilai IC50 yang didapat semakin kecil yang menandakan bahwa aktivitas antioksidan semakin kuat.

References

Agraharam, G., Chandra, S., & Saikia, B. (2022). Myricetin: A multifunctional flavonol in biomedicine. Current Nutrition & Food Science, 18(4), 403–421.

Anurukvorakun, O., & Numnim, S. (2023). Development and clinical efficacy evaluation of facial toner containing Houttuynia cordata Thunb. Cosmetics, 10(5), 133.

Cano, A., Maestre, A. B., Hernández-Ruiz, J., & Arnao, M. B. (2023). ABTS/TAC methodology: Main milestones and recent applications. Processes, 11(1), 185.

Cao, S., Liang, J., Chen, M., Xu, C., Wang, X., Qiu, L., & Hu, W. (2025). Comparative analysis of extraction technologies for plant extracts and absolutes. Frontiers in Chemistry, 13, 1536590.

Chatur, V. M., Walode, S. G., Awate, S. A., Gandhi, M. U., & Thorat, V. S. (2021). Formulation and physical characterization of herbal face gel toner. World Journal of Advanced Research and Reviews, 11(1), 138-145.

Chow, E. Y., & Elliott, J. F. (2024). Presence/Absence of Propylene Glycol in Commonly Used Topical Products in the Dermatology Clinic. Journal of Cutaneous Medicine and Surgery, 28(2), 192-193.

Gawali, N., Lande, V., Popalghat, D., Gavhane, K., Kharat, M., Bhagat, K., ... & Fitawe, P. (2025). Formulation and Evaluation of Herbal Facial Toner. International Journal of Scientific Research and Technology.

George, J., Edwards, D., Pun, S., & Williams, D. (2022). Evaluation of antioxidant capacity (ABTS and CUPRAC) and total phenolic content (Folin‐Ciocalteu) assays of selected fruit, vegetables, and spices. International Journal of Food Science, 2022(1), 2581470.

Gu, X., Li, Z., & Su, J. (2024). Air pollution and skin diseases: a comprehensive evaluation of the associated mechanism. Ecotoxicology and Environmental Safety, 278, 116429.

Han, H. S., Seok, J., & Park, K. Y. (2025). Air Pollution and Skin Diseases. Annals of Dermatology, 37(2), 53.

HAYKAL, D., Lim, H. W., Calzavara-Pinton, P., Fluhr, J., Cartier, H., & Berardesca, E. (2025). The Impact of Pollution and Climate Change on Skin Health: Mechanisms, Protective Strategies, and Future Directions. JAAD Reviews.

Imran, M., Saeed, F., Hussain, G., Imran, A., Mehmood, Z., Gondal, T. A., ... & Islam, S. (2021). Myricetin: A comprehensive review on its biological potentials. Food science & nutrition, 9(10), 5854-5868.

López, A. M., & da Silva Souza, I. (2025). Facial Toner Containing 2% Arbutin and 3% Niacinamide Improves Pore Appearance, Uneven Skin Texture, and Skin Brightness Measured by Individual Typology Angle.

Lubis, F., Lenny, S., & Sembiring, H. B. (2024). Antioxidants activity of face toner from ethyl acetate fraction of okra seeds. Journal of The Indonesian Society of Integrated Chemistry, 16(2), 109-114.

Madnani, N., Deo, J., Dalal, K., Benjamin, B., Murthy, V. V., Hegde, R., & Shetty, T. (2024). Revitalizing the skin: Exploring the role of barrier repair moisturizers. Journal of Cosmetic Dermatology, 23(5), 1533-1540.

Niisato, N., & Marunaka, Y. (2023). Therapeutic potential of multifunctional myricetin for treatment of type 2 diabetes mellitus. Frontiers in Nutrition, 10, 1175660.

Nuraeni, S., Supangkat, B., & Iskandar, J. (2022). Kajian etnobotani tanaman rempah sebagai bumbu, obat dan kias. Umbara, 7(1), 27-38.

Nurhidayanto, R. D., Pratiwi, D., & Rusdiana, N. (2025). ANTIOXIDANT TEST OF TONER IN SKINCARE PACKAGES CIRCULATING IN INDONESIAN SOCIETY. Journal of Fundamental and Applied Pharmaceutical Science, 5(2), 126-143.

Prakash, J., Sallaram, S., Martin, A., Veeranna, R. P., & Peddha, M. S. (2022). Phytochemical and functional characterization of different parts of the Garcinia xanthochymus fruit. ACS omega, 7(24), 21172-21182.

Rahmadani, N., Soendjoto, M. A., & Dharmono, D. (2021). Kajian Etnobotani Tumbuhan Famili Clusiaceae di Kawasan Kebun Raya Banua Banjarbaru, Kalimantan Selatan, Indonesia. Agro Bali: Agricultural Journal, 5(1), 57-66.

Sadsyam, S., Auliah, N., Uko, W. O. W. A., Basir, N., & Utari, A. U. (2023). Antioxidant evaluation of facial toner formulations containing ethyl acetate fraction from Garcinia mangostana L. Fruit using ABTS 2, 2'-azinobis 3-ethyl benzothiazoline 6-sulphonic acid method. Journal of Health Sciences and Medical Development, 2(02), 94-105.

Safitri, M., Sauri, S., Kuncoro, B., & Aprilliani, A. (2024). Formulation and antioxidant activity test of face toner extract preparation from 70% ethanol of cucumber fruit (Cucumis sativus L.). Jurnal Farmasi Sains dan Praktis, 122-134

Sun, Q., Wu, J., Qian, G., & Cheng, H. (2022). Effectiveness of dietary supplement for skin moisturizing in healthy adults: a systematic review and meta-analysis of randomized controlled trials. Frontiers in nutrition, 9, 895192.

Tan, I. J., & Lio, P. A. (2024). From Discovery to Modern Understanding: The Acid Mantle in Dermatology: The acid mantle plays a significant role in the skin barrier, pH balance, and microbiome. Understanding its function has advanced holistic skincare and therapeutic potential in dermatology. Journal of Integrative Dermatology.

Tourabi, M., Faiz, K., Ezzouggari, R., Louasté, B., Merzouki, M., Dauelbait, M., & Derwich, E. (2025). Optimization of extraction process and solvent polarities to enhance the recovery of phytochemical compounds, nutritional content, and biofunctional properties of Mentha longifolia L. extracts. Bioresources and Bioprocessing, 12(1), 24.

Windayani, N. R., & Pritasari, O. K. (2021, December). Analysis of Date Water Toner to Brighten Dry Facial Skin. In International Joint Conference on Arts and Humanities 2021 (IJCAH 2021) (pp. 950-953). Atlantis Press.

Winata, H. S., Faisal, H., Andry, M., Aulia, N., Nasution, M. A., & Tambunan, I. J. (2023). Penetapan kadar flavonoid total ekstrak etanol buah asam kandis (Garcinia xanthochymus) dengan metode spektrofotometri Uv-Vis dan LCMS. Journal of Pharmaceutical and Sciences, 935-950.

Ziemlewska, A., Nizioł-Łukaszewska, Z., Zagórska-Dziok, M., Mokrzyńska, A., Krupski, W., Wójciak, M., & Sowa, I. (2025). Anti-Aging, Anti-Inflammatory, and Cytoprotective Properties of Lactobacillus-and Kombucha-Fermented C. pepo L. Peel and Pulp Extracts with Prototype Skin Toner Development. Molecules, 30(20), 4082.

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Published

12-02-2026

How to Cite

ANTIOXIDANT EVALUATION AND MOISTURIZING EFFICACY OF FACIAL TONER PREPARATIONS FROM ASAM KANDIS ETHANOL EXTRACT: FORMULASI DAN EVALUASI TONER WAJAH ASAM KANDIS SEBAGAI ANTIOKSIDAN DAN PELEMBAB ALAMI DARI EKSTRAK ETANOL ASAM KANDIS (Garcinia xanthochymus) Hook.f. ex T. Anderson. (2026). Forte Journal, 6(1), 178-192. https://doi.org/10.51771/fj.v6i1.1900