PLESTER HIDROGEL ANTIJERAWAT DARI EKSTRAK BATANG TANAMAN JARAK (Jatropha curcas. L): PLESTER HIDROGEL ANTIJERAWAT

Embun Suci Nasution; Nabyla Ummil Husna; Dicky Syah Putra; Ardiansyah Putra; Wisnu Junior Butar-butar; Rahmatsyah Karo-karo

doi:10.51771/fj.v6i1.2108

Authors

Embun Suci Nasution Universitas Sumatera Utara
Nabyla Universitas Sumatera Utara https://orcid.org/0009-0002-8526-6387
Dicky Syah Putra Universitas Sumatera Utara
Ardiansyah Putra Universitas Sumatera Utara
Wisnu Junior Butar-butar Universitas Sumatera Utara
Rahmatsyah Karo-karo Universitas Sumatera Utara https://orcid.org/0009-0007-0744-894X

DOI:

https://doi.org/10.51771/fj.v6i1.2108

Keywords:

Antiacne, Antibacterial, Jatropha, Hydrogel Plaster

Abstract

People have used the sap of the castor plant (Jatropha curcas L.) as a treatment for acne, mouth ulcers, wound care, and to stop bleeding. Hydrogel plasters are sterile, able to absorb water, have a soft texture, are non-toxic, have the ability to help wound healing, are strong but quite elastic, can adhere well to the wound area, and do not cause scar tissue formation. This study aims to examine the efficacy of ethanol extract from the stem of the castor plant (Jatropha curcas L.) as an anti-acne using hydrogel technology. Ethanol extract of the stem of the castor plant (Jatropha curcas L.) contains secondary metabolites, namely flavonoids, glycosides, saponins, and triterpenes/steroids. Ethanol extract of the stem of the castor plant (Jatropha curcas L.) has antibacterial activity in the moderate category with inhibition zone diameters of 8.2 mm and 8.6 mm at the lowest concentration (6.25 mg/mL). The ethanol extract of Jatropha curcas L. stems has moderate antioxidant activity (IC₅₀ = 114.7055 mcg/mL). There were no side effects, such as redness, itching, or roughness of the skin, in 50 volunteers in the irritation test. Ethanol extract of Jatropha curcas L. stem has anti-acne properties, which can increase moisture content, increase smoothness (evenness), reduce pores, and reduce spots in volunteers. Hydrogel technology, used as plaster preparations on facial skin for anti-acne treatment, represents one of the latest and leading innovations in improving facial skin cleanliness and health.

Author Biography

Rahmatsyah Karo-karo, Universitas Sumatera Utara

B

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ANTI-ACNE HYDROGEL PATCH FROM JATROPHA (Jatropha Curcas L.) STEM EXTRACT