ANTIOXIDANT ACTIVITY TEST AND SPF VALUE DETERMINATION OF NANOCREAM ETHANOLIC EXTRACT OF MIMOSA PUDIC (Mimosa pudica L.) LEAF
UJI AKTIVITAS ANTIOKSIDAN DAN PENENTUAN NILAI SPF NANOKRIM EKSTRAK ETANOL DAUN PUTRI MALU (Mimosa pudica L.)
DOI:
https://doi.org/10.51771/fj.v6i1.2203Keywords:
Putri malu leaf, antioxidant activity, Sun Protection Factor (SPF)Abstract
The market has begun to circulate nano-sized cosmetics that are expected to be more effective in giving effect, in addition to providing more optimal results in skin care. This technology can also help in product stability and extend shelf life. The purpose of this study was to formulate ethanol extract of putri malu leaves into a nanocream preparation with various concentrations, and determine the ability of nanocream of ethanol extract of putri malu leaves as an antioxidant and sunscreen cream. The method used in this research is experimental method. This research was conducted with several stages of work, namely sample collection, sample identification, sample processing, simplisia characterization of putri malu leaves, phytochemical screening, making ethanol extract of putri malu leaves (Mimosa pudica L.) by maceration using 96% ethanol solvent, antioxidant activity test using DPPH method, determination of SPF value of ethanol extract of putri malu leaves, making nanocream preparation and particle size. Evaluation of cream preparation includes organoleptic examination, homogeneity of preparation, pH test of preparation, spreadability test, adhesion test, viscosity test, antioxidant activity test and determination of SPF value using UV-Vis spectrophotometer. The results of making nanocream of ethanol extract of putri malu leaves have antioxidant activity. The nanoparticle measurements obtained were (F0) 190.58 nm; (F1) 191.13 nm; (F2) 231.91 nm; (F3) 337.05 nm. The IC50 values were (F0) 52.6582; (F1) 37.5546; (F2) 36.8657; (F3) 34.9200, respectively. As a reference, the evaluation of the vitamin C solution resulted in an IC50 value of 2.8181. In vitro tests, the nanocream from the ethanol extract of mimosa pudica leaves obtained SPF values of (F0) 14.0233; (F1) 20.7968; (F2) 31.2993 and (F3) 40.6914. Each concentration had an SPF value above 15, so it can be categorized as ultra.
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