PEDIATRIC PATHOLOGICAL HUMERUS FRACTURE WITH SUSPECTED ANEURYSMAL BONE CYST: A CLINICAL PHARMACY REVIEW
FRAKTUR PATOLOGIS HUMERUS ANAK DENGAN KECURIGAAN KISTA TULANG ANEURISMAL: LAPORAN KASUS DAN TINJAUAN FARMASI KLINIS
DOI:
https://doi.org/10.51771/fj.v6i02.2397Keywords:
Fraktur Patologis, Humerus, Kista Tulang Aneurismal, Farmasi Klinis, CPPTAbstract
Fraktur patologis pada anak merupakan kondisi yang memerlukan evaluasi menyeluruh karena dapat berkaitan dengan lesi tulang jinak maupun ganas, termasuk kista tulang aneurismal. Artikel ini disusun sebagai laporan kasus deskriptif disertai telaah farmasi klinis pada pasien perempuan berusia 11 tahun 6 bulan dengan nyeri lengan kanan atas setelah trauma ringan saat berlari. Pasien didiagnosis mengalami fraktur patologis humerus kanan dengan kecurigaan tumor tulang primer akibat kista tulang aneurismal. Pasien menjalani open reduction internal fixation (ORIF) humerus, wide
excision, dan bone graft pada 14 Maret 2023, kemudian memperoleh terapi cairan Ringer laktat, parasetamol, seftriakson, ketorolak, dan ranitidin selama perawatan. Telaah farmasi klinis mengidentifikasi lima temuan utama Drug Related Problems (DRP), yaitu potensi inkompatibilitas seftriakson dengan Ringer laktat, kebutuhan pemantauan nyeri dan respons pascaoperasi, evaluasi leukositosis pascaoperasi, keamanan penggunaan ketorolak sebagai analgesik jangka pendek, serta kejelasan indikasi ranitidin. Berdasarkan temuan tersebut, apoteker klinis merekomendasikan penggantian seftriakson menjadi sefotaksim untuk menghindari risiko presipitasi, pemantauan
nyeri dan tanda infeksi secara terukur, evaluasi keamanan gastrointestinal serta ginjal selama penggunaan ketorolak, dan penegasan indikasi ranitidin dalam dokumentasi CPPT. Kasus ini menunjukkan bahwa keterlibatan apoteker klinis dapat meningkatkan keselamatan terapi dan mendukung kesinambungan pelayanan pada pasien fraktur patologis anak.
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