FORMULATION AND ANTIBACTERIAL ACTIVITY TEST OF THE PREPARATION CROWN ETHANOL EXTRACT SHOWER GEL PINEAPPLE (Apineapple comosus (L.) Merr) AGAINST BACTERIA Staphylococcus aureus

Christica Ilsanna Surbakti; Trinitatis Talunohi

doi:10.51771/fj.v4i2.930

Authors

Christica Ilsanna Surbakti Faculty of Pharmacy and Health Sciences, Universitas Sari Mutiara Indonesia
Trinitatis Talunohi Faculty of Pharmacy and Health Sciences, Universitas Sari Mutiara Indonesia

DOI:

https://doi.org/10.51771/fj.v4i2.930

Keywords:

Shower Soap, Pineapple Crown, Staphylococcus aureus, Antibacterial

Abstract

Antibacterial bath soap is in great demand by the public. This is because it is believed to cleanse the skin and can also treat or prevent diseases caused by bacteria. One of the natural ingredients that are efficacious as a natural anti-bacterial is pineapple crown. Pineapple crown extract has secondary metabolites namely alkaloids, flavonoids, tannins, saponins and triterpenoids/steroids. The purpose of this study was to determine the formulation of liquid bath soap preparations with the use of pineapple crown ethanol extract (ananas comosus (l.) Merr) as liquid bath soap and to determine the potential of pineapple crown ethanol extract liquid bath soap (ananas comosus (l.) Merr) to have antibacterial properties against staphylococcus aureus bacteria. The type of research carried out is an experimental method. The work procedure consists of sample preparation, sample identification, simplisia making, characteristic examination, phytochemical screening, extract making, making liquid shower soap preparations, evaluating liquid shower soap preparations and antibacterial activity tests against staphylococcus aureus bacteria. Pineapple crown ethanol extract is formulated in a shower soap preparation whose formulation uses concentrations of 3%, 5% and 7%. The results of the characterization of pineapple crown simplisia showed a moisture content of 9.50%, water-soluble juice content of 19.88%, soluble juice content in ethanol 13.30%, total ash content of 6.76%, acid insoluble ash content of 1.19%. The results of phytochemical screening testing show pineapple crown contains alkaloids, flavonoids, tannins, saponins, triterpenoids/steroids.

References

Aulifa, D.L., Febriani, Y., & Rendo, M.S. (2015). Aktivitas Antibakteri Ekstrak N-Heksan, Etil Asetat, dan Etanol Morus Alba.L terhadap Bakteri Penyebab karies gigi. Indonesian Journal of Pharmaceutical Sciences and tecnology (JSTFI), 2022.

Dalimunthe, G.I., Sutrisna, B.J., Rani, Z., & Ginting, O.S. (2024). Formulasi Dan Evaluasi Sediaan Sabun Sari Pepaya (Carica papaya L) Sebagai Pelembab. Forte Journal 4 (1), 251-260.

Ginting, O.S. (2017). Perbandingan Aktivitas Antibakteri Ekstrak Etanol Biji Pepaya (Carica papaya L.) Dari Dua Varietas Terhadap Bakteri Escherichia coli. Jurnal STIKNA, Vol. 1, No.2, 183-188.

Ginting, O.S., Rambe, R., Athaillah, & Mahara, P. (2021). Formulasi Sediaan Sampo Anti Ketombe Ekstrak Daun Binahong (Anredera cordifilia (Tenore) Steen)Terhadap Aktivitas Jamur Candida albicans Secara In Vitro. Forte Journal, Vol 1, No. 1, 57-68.

Ginting, O.S. (2021). Perbandingan Aktivitas Antibakteri Ekstrak Etanol Biji Pepaya (Carica papaya L.) Terhadap Bakteri Escherichia coli Dan Staphylococcus aureus. Forte Journal, Vol 1, No. 1, 19-25.

Ginting, O.S., & Siregar, S.S. (2022). Formulasi Dan Evaluasi Sediaan Masker Clay Dari Kombinasi Ekstrak Etanol Daun Pepaya (Carita papaya L.) Dan Labu Kuning (Cucurbita moschata). Forte Journal, Vol 2, No. 1, 22-31.

Ginting, O.S., Rambe., R., & Chairunnisa, R. (2023). Formulation of Ginger Candy (Zingiber officinale) From the Cultivation of Family Medicinal Plants (FMP) as an Antioxidant. Journal Of Pharmaceutical And Sciences, Vol. 6, No.1, 71-75.

Hutauruk, H., Yamlean, P. V. Y., & Wiyono, W. (2020). Formulation and activity test of celery herb ethanol extract liquid soap (Apium graveolens L) AGAINST STAPHYLOCOCCUS AUREUS BACTERIA. Pharmacon, 9(1), 73. https://doi.org/10.35799/pha.9.2020.27412

Irmayanti, P. Y., Wijayanti, N. P. A. D., & Arisanti, C. I. S. (2014). Optimization of the formula of liquid bath soap preparations from mangosteen peel extract (Garcinia mangostana Linn.). Journal of Chemistry, 8(2), 237–242. https://doi.org/10.24843/JCHEM.2014.v08.i02.p15

Jahan, N., Aslam, S., Rahman, K.ur Fazal T., Anwar, F., & Saher, R. (2016). Formulation and characterization of nanosuspension of herbal extracts for enhanced antiradical potential. Journal of Experimentl Nanosciences, 11(1), 72-80.

Jawetz, Melnick ad Adelberg. (2003). Mikrobiologi Kedokteran, Jilid I, Edisi XXII. Jakarta. Salemba Medika.

Laksana, K. P., Oktavillariantika, A. A. I. A. S., Pratiwi, N. L. P. A., Wijayanti, N. P. A. D., Yustiantara, P. S., Wife, A. A., Oktavillariantika, A. S., Pharmacy, J., Mathematics, F., & Knowledge, I. (2017). OPTIMIZATION OF HPMC CONCENTRATION ON THE PHYSICAL QUALITY OF MENTHOL LIQUID SOAP PREPARATIONS. Udayana Journal of Pharmacy, 6 No. 1(ISSN 2301-7716), 1–22.

Legi, A. P., Edy, H. J., & Abdullah, S. S. (2021). Formulation And Antibacterial Test For Liquid Soap With Ethanol Extract Of Soursop Leaves ( Annona).

Nayak, H B., Mohanty, B., Roy, H., & Patnaik, A. (2022). Nanosuspension: Bioavailability Enchancing Novel Approach. International Journal of Pharmacy and Biological. Sciences, 8

Pessoa, L., Duarte, J.L., Ferrreria, R.M., Oliveira, A. E., & Cruz, R.A. (2023). Nanosuspension of quercetin: preparation, characterization and effects againts Aedes aegypti larvae. Brazillian Journal of Pharcognosy, 28, 618-625.

Retnowati Y, Bialangi N, & Posangi NW. (2011). Growth of Staphylococcus aureus bacteria on media exposed with infusion of sambiloto leaves (Andrographis paniculata). 6(2):1-9.

Suerni, E., Alwi, M., & Guli, M.M. (2013). Uji Daya Hambat Ekstrak Buah Nanas (Ananas comosus L. Merr), Salak (Sallaca edults Reinw) dan Mangga kweni (Mangifera odorata Griff.) terhadap Daya Hambat Staphylococcus aures. Jurnal Bioclebes. 2013 (Vol. 7. No 1).

Tambunan, M.L., Sitompul, E., & Ginting, O.S. (2018). Perbandingan Aktivitas Antibakteri Ekstrak Etanol dan Ekstrak n-Heksana Biji Pepaya (Carica papaya L.) Terhadap Bakteri Escherichia coli. Jurnal STIKNA, Vol. 2, No. 1, 1-6.

Widyasanti, A., & Rohani, J. M. (2017). Making transparent solid soap based on olive oil with the addition of white tea extract. Journal of Tea and Quinine Research, 20(1), 13–29.